Modalert 200 increases brain wakefulness and alertness. Dopamine, norepinephrine, and histamine, which govern sleep-wake cycles and cognition, are affected. Modalert prolongs wakefulness and attentiveness by raising dopamine levels and decreasing its reuptake. The medicine mostly treats narcolepsy, sleep apnea, and shift work sleep disorder. Off-label use may increase focus, memory, and decision-making in healthy people.